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BV also alters cell shape, resulting in DNA and protein disintegration (Jung et al., 2018)

The peptide's exceptional selectivity for senescent cells, combined with its well-characterized mechanism of FOXO4-p53 interaction disruption, provides researchers with powerful capabilities for investigating senescence biology that were previously impossible to study

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It is a synthetic analogue of the C-terminal fragment of human growth hormone specifically amino acids 177191

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Main Research Findings 1) Treatment with FOXO4-DRI was found to reduce age-related testosterone secretion insufficiency in aged animals by targeting Leydig cells